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Clinical trials have demonstrated that Ozempic significantly reduces HbA1c levels and body weight compared with placebo and several active comparators

However, the reduced risks of hospitalized hypoglycemia and all-cause mortality associated with the use of a GLP-1RA versus insulin may lead to a favorable cost-utility profile for using a GLP-1RA

A subset of selenoproteins such as GPX1 and SELENOW is more sensitive to selenium supplementation or deficiency