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In the context of airway epithelial injury, 13-HODE was shown to induce hyperresponsiveness, cell damage, and neutrophilia 59,79

References state that the dysbiosis is likely to be responsible for early stage PD GI-related problems, including constipation, with a notable increase in bacterial families that include Lactobacillaceae, Verrucomicrobiaceae, Bradyrhizobiaceae, Bifidobacterium , and Akkermansia (Hashish and Salama, 2023)

Dysbiosis coupled with disturbance of the intestinal barrier leads to release of endotoxins from the lumen of the gut into the circulation and it enters the liver via the portal vein (Figure 3)

10.1093/toxsci/kfi280

Significant relationship between the LAT1 expression pattern and chemoresistance in ovarian clear cell carcinoma