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In the UK, cyanocobalamin is commonly used for oral supplementation due to its stability and effectiveness, whilst hydroxocobalamin injections are the preferred treatment for confirmed deficiency, particularly in pernicious anaemia or malabsorption conditions
Certain medical conditions and medications increase B12 requirements: Long-term use of metformin (diabetes medication) or proton pump inhibitors (PPIs for acid reflux) can impair B12 absorption [13] [14] Gastrointestinal conditions such as Crohn's disease, coeliac disease, or previous gastric surgery Autoimmune conditions beyond pernicious anaemia may affect B12 metabolism When to contact your GP : If you are taking B12 supplements or receiving injections but continue to experience symptoms, request a review
In a patient with normal B12 status, injecting more of it does not create surplus energy or burn fat
Individual variation is significant, and some people respond faster than others
This nutrient is required for fat metabolism and injecting more of this nutrient causes fat loss are different claims, and only the first is supported
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