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The retarded leaching of nanoclusters can be attributed to their large size in comparison with molecular dyes and it is a clear advantage for imaging purposes as dye leaching decreases the fluorescence brightness of NPs and increases the background signal resulting in unfavorable imaging inefficiency/artifacts 50

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TSLP is abundantly expressed in keratinocytes of AD lesions and promotes Th2-type inflammation while directly activating transient receptor potential ankyrin 1 (TRPA1) channels on sensory neurons, enhancing pruritus (Wilson et al., 2013

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