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Together, these findings indicate that CSF metabolomic profiles can capture treatment-relevant biological states that are reproducible, biologically coherent, and accessible through clinically feasible sampling strategies

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These polysaccharides promote M2 macrophage polarization, characterized by increased IL-10 production, while concurrently suppressing Th17 activation and IL-17 production (68, 71)

Glass bottom dishes were used for cell culture due to confocal scanning requirements

206 Prebiotics Prebiotics, a subset of soluble fiber, have gained attention for their ability to be selectively fermented by gut flora for a variety of potential health-promoting benefits