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Mental preparation for the recovery phase, along with maintaining a stable weight for six months before the procedure, are key considerations for those contemplating gynecomastia surgery after using semaglutide

Semaglutide is usually prescribed for people with a BMI of 30 or higher, or for people with a BMI of 27 or higher who have other Health problems related to their weight

That said, persistent, painful, or significant cycle changes should be reported to a healthcare professional

PIONEER 1: oral semaglutide for type 2 diabetes The PIONEER 1 trial tested oral semaglutide as monotherapy in people with type 2 diabetes over 26 weeks

In 2025, the agency also approved it to treat a serious form of liver disease known as metabolic-associated steatohepatitis (MASH), noting Wegovy's effect on the body may improve liver inflammation and scarring