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The short version: the combination appears safe for most patients, but your prescribing provider should know about both medications before you start either one

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The GLP-1 patch was the logical next step in that marketing evolution: take the same ingredients already being sold in capsules, put them in a transdermal patch (a format associated in consumers' minds with legitimate nicotine and hormone therapies), and market them with GLP-1 keywords

Vomiting occurred in 17% of participants at the 12 mg dose, compared to lower rates with Mazdutide