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Due to the lack of regulation, the chemical compounds in these device and e-liquids can vary between brands and do not have to be disclosed by manufacturers

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Methods: We prospectively re-evaluated COPD exacerbations, spirometric indices, subjective assessments (using the COPD Assessment Tool [CAT] scores), physical activity (measured by the 6-minute walk distance [6MWD]), and conventional cigarette use in EC users with COPD who were retrospectively assessed previously