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It is involved in many processes in the body including tissue building and repair, making chemicals and proteins needed in the body, and also an essential component of the bodys natural defence system (immune system)

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The psychological and emotional weight of managing this disease is heavy

In addition to the use of TKIs combined with PD-1/PD-L1 inhibitors, dual immunotherapies (ipilimumab with nebuliumab and atrilizumab with bevacizumab) are currently used for the first-line treatment of advanced renal cancer (166)

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