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While a specific l-citrulline transporter has not been identified, the B 0 -transporters have been suggested to play a role in the Na + dependent transport of l-citrulline across the enterocytes [30]
Enfermedades metablicas Las principales enfermedades metablicas que cursan con hepatomegalia(3) son: las glucogenosis (fundamentalmente I, III, VI y IX), las enfermedades lisosomales (enfermedades de Gaucher, de Niemann-Pick, de Wolman y por depsito de steres de colesterol, mucopolisacaridosis), los defectos de glicosilacin de protenas (CDG) y las enfermedades peroxisomales
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Animal As a senolytic, FOXO4-DRI carries mechanism-specific theoretical risks discussed in the senescence literature including disruption of beneficial senescence surveillance and off-target effects on stem-cell populations that share features with senescent cells and senolytic translation from mouse to human has a history of failures