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Onuma H, Inukai K, Kitahara A, Moriya R, Nishida S, Tanaka T, et al

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But most people with HLA-B27 do not develop ankylosing spondylitis, and it is not known how HLA-B27 increases AS risk

Clinical studies provide direct evidence: GLP-1 analogue therapy significantly reduced sCD163 (a marker of inflammatory macrophage activation), independent of changes in body weight, fructosamine, and HbA1c

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