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Schiaffino et al., 2013)

The SURMOUNT-1 trial data shows that late responders can take up to 25 weeks to achieve clinically meaningful results, so patience is critical

Folic acid remains an effective way to support one-carbon metabolism and lower homocysteine in most people, while methylfolate may offer advantages for some individuals, particularly those with reduced DHFR activity or a poor response to folic acid

A oggi, in Italia non ancora approvato per questa indicazione

Although vitamin C supplementation has not been shown to cause kidney stones in randomized controlled trials, it may nevertheless be prudent for people with a history of calcium oxalate kidney stones to consult a qualified healthcare provider before initiating supplementation with high-dose vitamin C