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The Food and Drug Administration has not approved any injectable medications for skin lightening, and its long term safety and effects have not been documented

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The glucagon receptor component, which drives energy expenditure, may offer a different durability profile compared to appetite-only mechanisms, but this remains a hypothesis under investigation rather than an established finding [5]

Last year, the FDA mandated a change to Ozempics label to mention the potential risk of ileus following adverse event reports, though it stopped short of confirming ileus as a side-effect

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