The people who deserve extra attention usually include: Patients with a known history of diabetic retinopathy Patients with diabetic macular edema Patients with recently worsening retinopathy Patients with poor baseline glucose control who may experience a large A1c drop Patients starting semaglutide while already under retina treatment Patients with multiple high-risk features such as kidney disease, hypertension, or long-standing diabetes In contrast, a patient with type 2 diabetes, no known retinopathy, and a recent normal dilated exam may still need routine follow-upbut often not the same level of concern as someone with active retinal disease
In terms of weight loss, cotadutide 200 g produced effects similar to liraglutide, while the 300-g dose resulted in greater weight reduction
doi:10.1016/j.eclinm.2024.102624 Palermo A, DOnofrio L, Eastell R, Schwartz AV, Pozzilli P, Napoli N
Although GLP-1 RA therapy has shown promising results for preserving lean mass and even muscle quality compared to fat mass, the trajectory of muscle mass and function following weight regain remains uncertain [98]
Shooting water directly onto the powder creates foam and can damage the peptide through mechanical stress