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The findings showed that participants with T2D lowered their HbA1c by 1.3% to 2.0% after taking 4- 12 mg retatrutide for about six months, compared to no change with placebo and a 1.4% HbA1c reduction with dulaglutide

FOXO4-DRI disrupts PML/DNA-SCARS and releases active p53 in senescent cells Interference with FOXO4 signaling could be a strategy to eliminate senescent cells and thereby potentially target senescence-related diseases