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If left untreated, NASH can progress to more serious liver conditions, including fibrosis, cirrhosis, and potentially liver cancer, which may result in hepatocellular carcinoma and hepatic complications like ascites, encephalopathy, and variceal bleeding, leading causes of death globally [167]

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Studies suggest that certain genetic variations may heighten the risk of depression in high-stress environments, while having little effect in low-stress settings [306]

Protocol tracking and adjustment adds ongoing time commitment

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