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Large-scale clinical trials have demonstrated that these modern metabolic treatments are highly effective, with semaglutide patients losing an average of 15% to 20% of their total body weight over 68 weeks

Call 999 or go to A&E immediately if experiencing: Cauda equina syndrome urinary retention or incontinence, loss of anal sphincter control, saddle anaesthesia (numbness around genitals/buttocks), bilateral sciatica, or progressive leg weakness [11] Severe, persistent abdominal pain radiating to the back (with or without vomiting) may indicate acute pancreatitis

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Recent studies revealed that over 2% of Americans are now using GLP-1 primarily for weight loss purposes