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Recently, the hNGPp peptide that harbors a mutation reducing the pro-nociceptive activity of NGF, delivered intranasally in mice, activated the TrkA and downstream Erk1/2, Akt pathways leading to neuroprotective and anti-amyloidogenic actions ( Statements Data availability statement All datasets generated for this study are included in the manuscript and/or the supplementary files
Therefore, our results are in line with previous findings that GST inhibition by DEM does not increase the toxicity of neonicotinoids to insects and related organisms like springtails
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