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The activation of microglial cells by A deposition promotes the production of proinflammatory and cytotoxic factors, such as TNF-, IL-1, IL-6, interferon-gamma (IFN-), transforming beta growth factor (TGF-), chemokines and macrophage inflammatory protein (Yan et al., 2021)

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Purification and Detection High performance liquid chromatography (HPLC) purification: The synthesized polypeptides need to be purified by HPLC to remove impurities and unreacted raw materials, ensuring that the purity meets the pharmaceutic-grade standard

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