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Apart from WEGOVY, SAXENDA , another Novo Nordisk weight loss drug, is also approved in the US for obesity

Ubiquitin-specific protease 19 regulates the stability of the E3 ubiquitin ligase MARCH6

When it became clear that semaglutide also helped people lose weight, and lots of it, scientists thought what made it so effective was how it can work in the gut, slowing down digestion, and as a result, decreasing appetite