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For adult smokers comparing cigarette products, the difference between light, smooth, silver, and regular cigarettes is mainly about smoking preference, flavour profile, and perceived strength not safety

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4-HNE expression was also significantly decreased in NCOA4 siRNA treated BEC, indicating attenuated lipid peroxidation can be attributed to less ferritin degradation with concomitantly reduced Fenton type reactions in the setting of NCOA4 reduction (Supplementary Fig