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69 Small molecules including tyrosine kinase inhibitors targeting KIT, Btk, and JAK inhibitors as well as biologics targeting MC inhibitory receptors such as Siglec molecules require further exploration

By screening in four different media conditions, we uncovered their metabolic regulation, including the fitness defects in the mitochondrial folate transporter SLC25A32 KO cells that can be buffered in galactose condition due to substrate limitation in de novo purine biosynthesis

10.1007/s12672-014-0188-8 171 WangH.LiuK.GengM.GaoP.WuX.HaiY.et al (2013)

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A meta-analysis of animal studies showed KD significantly extended survival time and reduced tumor weight [138]