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These oxidatively modified proteins can acquire neoantigen properties - meaning the immune system no longer recognizes them as "self" and mounts an antibody response against them

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Therefore, using a large, real-world population with type 2 diabetes, we constructed a model to assess the cost-effectiveness of widespread use of SGLT2is and GLP-1 RAs in people with type 2 diabetes, considering only major cardiovascular and kidney outcomes

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