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Approvals will be in effect for a limited time, e.g., 10 years, and will be eligible for renewal in the absence of significant changes in agricultural or industry practices (e.g., a change occurs in a predominant variety produced)

Brain Behav

Although this amount is small compared with the annual economic losses from tobacco ($1.4 trillion per year) and may appear insignificant compared with the 8 million deaths attributable to tobacco each year, these environmental costs should not be downplayed as these are accumulating and are preventable, Sy said in a news release

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More significantly, nicotine alternatives are improving profitability