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Applications of genome editing technology in the targeted therapy of human diseases: Mechanisms, advances and prospects

For whereas men of an older school, like myself, smoke for the pleasure of smoking, men of this school smoke for the pleasure of pipe-owningof selecting which of their many white-spotted pipes they will fill with their specially-blended tobacco, of filling the one so chosen, of lighting it, of taking it from the mouth to gaze lovingly at the white spot and thus letting it go out, of lighting it again and letting it go out again, of polishing it up with their own special polisher and putting it to bed, and then the pleasure of beginning all over again with another white- spotted one

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but it became somewhat of a chore for Malia and Sasha, who had to endure their father's quirky puns

'It doesn't suck,' he admits