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Brand name was also masked on the cigarette sticks that participants were shown in this portion of the study, minimizing the potential influence of brand on this particular selection task

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We indicate proportionately more younger participants in certain spliff usage groups, possibly related to our outcome variable

The observed lack of a significant accumulation of PHN in brain following the intraventricular administration of (+)-amphetamine and the formation of appreciable amounts of PHN from (+)-POH in brain tissue in vivo supports the view that the aromatic hydroxylation of amphetamine following its systemic administration occurs predominantly in the periphery, and that POH is then transported through the blood-brain barrier, taken up by noradrenergic neurones in brain where (+)-POH is converted in the storage vesicles by dopamine -hydroxylase to PHN