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In addition to the liver, there is evidence suggesting the metabolism of nicotine and formation of cotinine in the brain, mechanisms of which remain less clear (Jacob et al., 1997)

By examining the genetic mutations across different lung cancer subtypes, geographic regions, and environmental exposures, the researchers illuminated previously hidden drivers of lung cancer in never smokers

The letter cited Massachusetts and California as examples of states that experienced illicit tobacco market growth after enacting laws banning the sale of flavored tobacco

10.21448/ijsm.1095643 479