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The chemicals and irritants in cigarettes cause swelling in the throat and the vocal tissues which can: Make your voice raspy Make your voice scratchy and rough Decrease your singing range Cause breathiness Weaken your voice Reduce pitch and tonal accuracy Increase vocal fatigue Cause bouts of coughing during the singing Some singers think a raspy, gravelly tone from smoking is desirable

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Short-period influence of chronic morphine exposure on serum levels of sexual hormones and spermatogenesis in rats

NRTs like nicotine patches can potentially impact blood pressure, though generally to a lesser extent than smoking