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Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements

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Unlike many nutrients, B12 is produced exclusively by bacteria and obtained primarily through animal-based foods including meat, fish, eggs, and dairy products

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Some users also highlight the compounds ability to target stubborn fat, with noticeable improvements in body composition over time