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36,37,38 Successful and durable weight loss with GLP-1 RAs is only possible with continued treatment

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GLP-1 medications can produce relatively rapid weight loss, which tends to increase the likelihood of excess skin compared to gradual loss through diet and exercise alone

And a fall, particularly later in life, can have serious consequences from fractures to long-term loss of independence

Among these, semaglutide has demonstrated reduced risk of major adverse cardiovascular events (MACE) in trial participants with moderate or high cardiovascular risk