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A., Oliver R

Human studies mirror this pattern, with identical nutrient loads eliciting significantly greater GLP-1 and GIP release in the morning than in the afternoon [9]

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Chronic hyperglycemia induces excessive accumulation of advanced glycation end products (AGEs), enhanced oxidative stress, activation of inflammatory responses, and aberrant activation of the renin-angiotensin system (RAS)

A 2023 safety trial (n=200) confirmed no hepatotoxicity or allergy beyond 1% (Babu et al., 2023)