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Zn has a significant role in the biochemistry and metabolism of plants owing to its significance and toxicity for biological systems at specific Zn concentrations, i.e., insufficient or harmful above the optimal range

However, it is an INCI-listed cosmetic ingredient widely used in skincare formulations

The clinical evidence behind that approval is specific and limited

The assessment of placebo groups in randomized controlled trials for melasma allows for measuring the efficacy of broad-spectrum tinted sunscreens, accounting for a 1020% melasma area and severity index (MASI) reduction in 8 weeks [19]