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The more melanin produced, the darker the skin becomes

However, controversy still exists as to whether it is best to therapeutically promote or inhibit GIP action for beneficial effects on glycemic control and body weight [[929], [930], [931]] as both GIPR agonists [932] and antagonists [933,934] have decreased body weight in preclinical studies as individual treatments, but also to induce synergistic body weight loss when combined with GLP-1R agonists

Medications for Vomiting (see the medications for nausea in medications for nausea and vomiting above) IV

Significant weight loss of any cause can produce telogen effluvium, a temporary shedding of hair that occurs two to three months after a significant physical stress