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HRD1 functions as a tumor suppressor in ovarian cancer by facilitating ubiquitination-dependent SLC7A11 degradation

10.1016/j.jep.2021.113866 697

151,152 GDH1 depletion results in imbalanced redox homeostasis and cell cytotoxicity and attenuates cancer cell proliferation, which as well as the results in erythroleukemia cells, while it negligibly affects normal cell proliferation

Mol Biol Cell 15(2):543551

Melatonin analogs UCM 976, UCM 1032, UCM 1033, UCM 1037) that target membrane receptors MT1 and MT2 showed an ability to inhibit the proliferation of DX3 melanoma cells and MCF-7 breast cancer cells, and MDA-MB231 in a dose- and time-dependent manner in viability assays