Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: a 24-week, randomized, placebo-controlled study (GetGoal-Duo 1)
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Abbreviations CD: Crohns disease DPP-IV: Dipeptidyl peptidase IV DSS: Dextran sulfate sodium EEC: Enteroendocrine cells GI: Gastrointestinal tract GIP: Gastro-insulinotropic peptide GLP: Glucagon-like peptide GM-CSF: Granulocyte-macrophage colony-stimulating factor IBD: Inflammatory bowel diseases IFN-: Interferon IGF-1: Insulin-like growth factor 1 IL: Interleukin LPS: Lipopolysaccharide PC 1/3: Prohormone convertase 1/3 PEG: Polyethylene glycosyl SCFA: Short-chain fatty acids TNBS: 2,4,6-trinitrobenzenesulfonic acid TNF-: Tumor necrosis factor UC: Ulcerative colitis References Abrahami D, Douros A, Yin H, et al (2018) Dipeptidyl peptidase-4 inhibitors and incidence of inflammatory bowel disease among patients with type 2 diabetes: population based cohort study
El Epithalon 10mg suele reconstituirse con 2 ml de agua bacteriosttica, obteniendo una solucin de trabajo de 5 mg/ml (5.000 mcg/ml)