Excessive inflammation can exacerbate bodily damage and impede recovery outcomes
aureus metalloproteinase aureolysin cleaves LL-37, while staphylokinase inhibits the bactericidal effect of defensins
It can be used as a standalone therapy for individuals seeking natural alternatives to conventional antidepressants or as an adjunct therapy alongside traditional medications, potentially enhancing overall treatment efficacy and reducing side effects
first discovered plasma intestinal flora-dependent small molecule metabolic spectrum by metabonomics and found that the plasma levels of TMAO and its precursors, choline and betaine, can predict the risk of human cardiovascular disease, thus identifying a novel relationship between intestinal flora and metabolic health ( In this paper, we describe in detail how TMAO promotes the transformation of macrophages to foam cells, which lead to reverse cholesterol transport that inhibits bile acid and sterol metabolism, and at the same time enhances the hyperactivity of platelets, which leads to the formation of atherosclerotic plaques
M.JouaninL.SiemsI.UchidaW.2010(2010) Chemistry and biochemistry of lipid peroxidation products
