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Native IGF-1, while powerful in its anabolic effects, has major limitations in research uses due to its short half-life of about 10 minutes and its high affinity for insulin-like growth factor binding proteins (IGFBPs), also known as igf-binding proteins

Recently, c-Myc has also been shown to contribute to the basal expression and induction of human GCL under conditions of oxidative stress

Lumbar spine BMD increased by approximately 11% over 18 months

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Wet beriberi, which refers to infantile thiamine deficiency, is characterized by cardiomyopathy, heart failure, warm extremities, and pulmonary edema, with early symptoms including fatigue, nausea, and mental suppression (, , )