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GSH depletion may result from environmental chemicals and toxins, infections, inflammation, poor nutrition and ageing - compromising the body's ability to defend against cellular damage

Metformin reverses fatty liver disease in obese, leptin-deficient mice

8-OHdG serves as a biomarker of oxidative stress in spermatozoa and has been linked to chromosomal instability and mutagenesis (67, 68)

Misuse and abuse of CNS stimulants, including VYVANSE, can result in overdose and death [see Overdosage (10)], and this risk is increased with higher doses or unapproved methods of administration, such as snorting or injection

[4] Rubino, D.M., et al