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Potent body weight loss, and therapeutic efficacy in a NASH animal model by a novel long-acting GLP-1/Glucagon/GIP tri-agonist (HM15211)

In the LIVE trial, liraglutide had no meaningful impact on SBP or left ventricular function in HFrEF but increased heart rate by approximately 7 beats per minute

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The mechanism and timeline are the same as for male patients, with some adjustments in the protocol for patients in perimenopause or menopause where hormonal changes affect collagen synthesis and healing rates

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