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Description

FDA approval requires clinical trials demonstrating safety and efficacy for a specific indication

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This structural modification significantly reduces its affinity for IGF binding proteins (IGFBPs), increases the free concentration, and enhances its biological activity by more than three times compared to natural IGF-1

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Saxenda was launched to market in the United States on April 22, 2015

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Registration This study was registered with Prospero with ID CRD42021251299

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Prolonged vomiting may also increase the risk of thiamine deficiency and other micronutrient abnormalities in this already vulnerable population

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