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Injections, topical gels, or pellets: Different delivery methods provide flexibility depending on how hands-on you want treatment to be and how steadily you prefer your hormone levels maintained

Ligand binding drives receptor autophosphorylation, IRS-1/IRS-2 adapter recruitment, and activation of two primary downstream cascades: PI3K/Akt/mTOR (governing protein synthesis, glucose uptake, and cell survival) and MAPK/ERK (regulating cell proliferation and differentiation)

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