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Techniques like ion-pairing reversed-phase liquid chromatography (IP-RPLC) are widely used to monitor peptide critical quality attributes (CQAs), with hyphenated LC-MS approaches playing a key role in enhancing sensitivity and selectivity, enabling quantification of low-level impurities

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Anti-inflammatory mechanisms have been explored through multiple signaling pathways, including nitric oxide modulation and growth factor expression

This pattern is problematic for several reasons

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