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They also reported that the SCN of rats in the TSI group had increased and decreased Rev-Erb and Bmal1 protein levels, respectively, in addition to neuronal mitochondrial dysfunction, compared with that of rats in the control group

Animal studies indicate dose-dependent effects, with toxic doses possibly affecting copper metabolism or interacting with embryonic development in hypersensitive models, warranting caution during pregnancy

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[DOI] [PubMed] [Google Scholar] 38.Side effects of a dopamine agonist therapy for Parkinson's disease: a mini-review of clinical pharmacology