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J Physiol Paris 1993;87(5):313-327

doi: 10.1038/nrn1886 217 MatuteC.AlberdiE.DomercqM.Snchez-GmezM.-V.Prez-SamartnA.Rodrguez-AntigedadA.et al

Direct interactions between RIPK3 and enzymes, such as the pyruvate dehydrogenase complex (PDH), glutamate-ammonia ligase (GLUL), glutamate dehydrogenase 1 (GLUD1), and glycogen phosphorylase L (PYGL), can enhance energy metabolism and promote mitochondrial ROS production, thereby augmenting necroptosis in cervical adenocarcinoma and colon cancer cells [134]