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The most common side effects are nausea, vomiting, diarrhea, and constipation especially during dose increases

Microdosing is used off-label to reduce the incidence of these side effects and improve the bodys tolerance

Moreover, in the SNI-induced chronic neuropathic pain model, heat hyperalgesia was alleviated in mice challenged with SNI and administered intraperitoneal injections of 50 g of exendin 2029, with effects observed as early as 1 hour postadministration and peaking at 2 hours compared with those in the vehicle-administered group (Supplementary Fig

Oral daily tablet that activates GLP-1 receptors without requiring injection