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However, a study (Zhakeer et al., 2017) of bufalin effect on asthmatic response in a mouse model, has demonstrated that this CTS (in a dose 5 and 10 mg/kg) significantly attenuated hyperresponsiveness and strongly suppressed the ovalbumin (OVA)-induced increase of total amount of inflammatory cells including macrophages, eosinophils, lymphocytes, and neutrophils in bronchoalveolar lavage fluid (BALF)

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Mouse research reported antinociceptive responses following central administration of DSIP

Int J Pharm Sci Invent 6:114 Zaheer Sameermahmood ZS et al (2008) Curcumin modulates SDF-1/CXCR4-induced migration of human retinal endothelial cells (HRECs) Deshpande J et al (2015) Soluble curcumin in the prevention of diabetic retinopathy via modulation of anti-oxidant activity and genetic pathwaysin vivo model