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For most people, theyre safe and effective for long-term health and weight management

Semaglutide remains highly effective for many people and may be preferred if you have sensitivities to GIP receptor activation or prefer a well-established single-pathway medication

523 Analysis of gene expression in cortical astrocytes from old mice identified an increase in genes linked to an immune response with a decrease in expression of GFAP and genes related to neuroprotection and neuronal support, 524 and the prominent up-regulation of genes contributing to synapse elimination in astrocytes from aged hippocampus and cerebellum

Most patients reach stable weight loss or plateau within 46 months of therapy

Sharps bins should be kept closed and stored safely out of reach of children