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Understanding Dual Agonism: The Tirzepatide Mechanism GIP and GLP-1 Receptor Biology Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 represent two key incretin hormones that regulate postprandial glucose homeostasis

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The composite heart failure endpoint (cardiovascular death or hospitalization/urgent visit for heart failure) showed a 21% reduction (hazard ratio 0.79)

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