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In addition, small molecule inhibitors including SLC7A11 inhibitor HG106 and GCLC inhibitor buthionine sulfoximine (BSO) were introduced to investigate their effects on ROS, GSH levels and cellular viability in VRK2-KO and VRK2-KD cells, and the results were consistent with the above knockdown experiment (Fig

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Pathway / Mechanistic Context In experimental and preclinical research literature, GHK-Cu is referenced in relation to copper-binding peptide signaling frameworks and cellular communication pathways examined at molecular and biochemical interaction levels

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