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During activation, T cells uptake glucose via the upregulation of Glut1 expression, followed by generation of energy to promote cytokine secretion.29, 30 Here, we provided several lines of evidence suggesting that acetaldehyde inhibits glucose metabolism in T cells via the downregulation of Glut1 expression and inhibition of several metabolic signalling pathways

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Available from Accessed 9 Apr 2025 Eeg-Olofsson K, Miftaraj M, Ann-Marie S et al (2021) National Diabetes Register, annual report 2020